System 02: Cell Cycle Model;Tyson (1991, 6 variables)


Specification

A model of the cell cycle based on the interactions between cdc2 and cyclin. The model has six dynamic variables: C2 (cdc2); CP (cdc2-P complex); pM (P- cyclin-cdc2-P complex); M (active MPF, P-cyclin- cdc2 complex); Y (cyclin); and YP (cyclin-P). Total cyclin concentration (YT) is the sum YT=Y+YP+pM+M

References

Tyson JJ. Modeling the cell division cycle: cdc2 and cyclin interactions, PNAS, 88: 7328-7332 (1991).

Cellerator Model repository page

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