The Biochemical Abstract Machine BIOCHAM 4

version 4.5.17 June 2021

Inria EPI Lifeware, Centre Inria Saclay Ile de France
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Biocham 4 was first released in September 2017.

Biocham 4 is a complete rewriting of Biocham 3 for easier maintenance. It integrates new features, in particular concerning the synthesis of reaction systems, robustness optimisation and influence systems. For the sake of reproducible research, Biocham 3 is still active on but no longer maintained. Biocham 0 was first released in 2002.


The Biochemical Abstract Machine (Biocham) is a modelling environment for systems biology and synthetic biology.

Biocham is mainly composed of :

Biocham is a free software protected by the GNU General Public License GPL version 2. This is an Open Source license that allows free usage of this software.

Feedback on the use of Biocham in applications, research or teaching are particularly welcomed.



Unique features

Biocham implements some unique features for:

Online access to notebook - Docker image download - Installation from source files

Feedback and bug reports: or mail to