Master Parisien de Recherche en Informatique (MPRI)
Within the MPRI master, I'm involved together with Francois Fages, Jean Krivine, and Denis Thieffry in the computational biology course. This course is primarily intended for computer scientists has a strong emphasis on mathematical and computational methods. Firstly, we show that understanding the functioning of biomolecular systems amounts to study uncertain high-dimensional non-linear dynamical system. Secondly, we introduce several methods developed in the hybrid system community to analyse such systems.
The slides corresponding to these lectures are available below.
- short presentations on the course, and more specifically on my part are available here and there.
- some material on the intro on biomolecular biology is available here [1st class]
- slides on (1) gene network modeling, (2) indirect approaches for PMADE systems for parameter synthesis and (3) their application to the desing of a transcriptional cascade are here [2nd and 3rd classes]
- slides for direct approaches for nonlinear models using hybridization are here [4th class]
Master Approches Interdisciplinaire du Vivant (AIV)
Within the AIV master, I'm involved in the computational biology course. The objective of the course is to present existing computational methods that are useful for model developement and model analysis. Such notions include deterministic and stochastic modeling, parameter search, and sensitivity analysis. The slides corresponding to past lectures are available on the combio website.